Molecular epidemiological analysis suggests cross-infection with Pseudomonas aeruginosa is rare in non-cystic fibrosis bronchiectasis.
نویسندگان
چکیده
1) Newcastle University, Institute of Cellular Medicine and 2) Sir William Leech Centre for Respiratory Research and Freeman Hospital Adult Bronchiectasis Unit, Newcastle upon Tyne Hospitals Trust, 3) Department of Medical Microbiology, The Newcastle upon Tyne Hospitals NHS Foundation Trust, 4) Institute of Infection and Global Health, University of Liverpool 5) Antibiotic Resistance and Healthcare Associated Infections Reference Unit, Public Health England, Colindale, London
منابع مشابه
Investigating the Presence of Type IV Pilin Subgenus in Pseudomonas Aeruginosa Isolated from Clinical and Non-Clinical Samples
Introduction: The type IV Pilin is an important colonization factor for opportunistic pathogens of Pseudomonas aeruginosa, which plays a role in the formation of biofilms and binding to the host cells. Each type of Pilin is coded with a particular auxiliary gene. This specific relationship can be used as a therapeutic target for detecting Pseudomonas aeruginosa strains as well as its molecular ...
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In patients with cystic fibrosis (CF) and non-CF bronchiectasis, Pseudomonas aeruginosa is the most important respiratory pathogen. It is able to synthesise hydrogen cyanide, a potent inhibitor of cellular respiration. The present study investigated whether cyanide is present in the sputum of CF and non-CF bronchiectasis patients infected with P. aeruginosa, and whether the detection of cyanide...
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Abstract Background and Objective: Cystic fibrosis (CF) is an autosomal recessive genetic disease and Pseudomonas aeruginosa is one of the most common bacteria colonized in CF patients. Growing resistance of this bacterium to antibiotics now a day is a challenge of controlling infection in CF patient. In this study colonization of CF patients with Pseudomonas aeruginosa and antibiotic suscep...
متن کاملCross-infection with Pseudomonas aeruginosa is rare in non-cystic fibrosis bronchiectasis http://ow.ly/sjvKz
Anthony De Soyza, Audrey Perry, Amanda J. Hall, Syba S. Sunny, Kathy E. Walton, Nazim Mustafa, Jane Turton, Dervla T. Kenna and Craig Winstanley Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, Sir William Leech Centre for Respiratory Research and Freeman Hospital Adult Bronchiectasis Unit, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, Dept o...
متن کاملIsolation and Genetic Fingerprinting of Pseudomonas aeruginosa from Iranian Patients with Cystic Fibrosis Using RAPD-PCR
Sixty four Iranian patients with cystic fibrosis (CF) were studied for colonization with Pseudomonasaeruginosa. The patient’s age ranged between 2 months to 18 years old. Twenty one patients werecolonized, 15 with non-mucoid and 6 with mucoid strains of P. aeruginosa. The colonization rateincreased with age and the mucoid phenotype was only recovered from the older patients. A...
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عنوان ژورنال:
- The European respiratory journal
دوره 43 3 شماره
صفحات -
تاریخ انتشار 2014